Authors: Skurikhin, Evgenii G. | Pershina, Olga | Ermakova, Natalia N. | Pakhomova, Angelina | Zhukova, Mariia | Pan, Edgar S. | Sandrikina, Lubov | Widera, Darius | Kogai, Lena | Kushlinskii, Nikolai | Kubatiev, Aslan A. | Morozov, Sergey G. | Dygai, Alexander M.

Source: International journal of molecular sciences. 2022. Vol. 23, № 24. P. 15780 (1-16)

Type: статьи в журналах

Date: 2022

Description: Using a model of Lewis lung carcinoma (LLC) in vitro and in vivo, we previously demonstrated increased antitumor activity in CD8+ T-cells reprogrammed with an MEK inhibitor and PD-1 blocker. In this f ... More

Authors: Skurikhin, Evgenii G. | Pershina, Olga | Ermakova, Natalia N. | Pakhomova, Angelina | Widera, Darius | Zhukova, Mariia | Pan, Edgar S. | Sandrikina, Lubov | Kogai, Lena | Kushlinskii, Nikolai | Morozov, Sergey G. | Kubatiev, Aslan A. | Dygai, Alexander M.

Source: Biomedicines. 2022. Vol. 10, № 6. P. 1450 (1-18)

Type: статьи в журналах

Date: 2022

Description: CD8+ T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes la ... More

Authors: Shiyan, Alexandra A. | Kapilevich, Leonid V. | Lopachev, Alexander V. | Fedorova, Tatiana N. | Klementieva, Tatiana S. | Moskovtsev, Aleksey A. | Kubatiev, Aslan A. | Orlov, Sergei N. | Smolyaninova, Larisa V.

Source: PLoS ONE. 2019. Vol. 14, № 9. P. e0222767 (1-23)

Type: статьи в журналах

Date: 2019

Description: It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other ... More