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Authors:
Skurikhin, Evgenii G. |
Pershina, Olga |
Ermakova, Natalia N. |
Pakhomova, Angelina |
Zhukova, Mariia |
Pan, Edgar S. |
Sandrikina, Lubov |
Widera, Darius |
Kogai, Lena |
Kushlinskii, Nikolai |
Kubatiev, Aslan A. |
Morozov, Sergey G. |
Dygai, Alexander M.
Source: International journal of molecular sciences. 2022. Vol. 23, № 24. P. 15780 (1-16)
Type: статьи в журналах
Date: 2022
Description:
Using a model of Lewis lung carcinoma (LLC) in vitro and in vivo, we previously demonstrated increased antitumor activity in CD8+ T-cells reprogrammed with an MEK inhibitor and PD-1 blocker. In this f
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Authors:
Skurikhin, Evgenii G. |
Pershina, Olga |
Ermakova, Natalia N. |
Pakhomova, Angelina |
Widera, Darius |
Zhukova, Mariia |
Pan, Edgar S. |
Sandrikina, Lubov |
Kogai, Lena |
Kushlinskii, Nikolai |
Morozov, Sergey G. |
Kubatiev, Aslan A. |
Dygai, Alexander M.
Source: Biomedicines. 2022. Vol. 10, № 6. P. 1450 (1-18)
Type: статьи в журналах
Date: 2022
Description:
CD8+ T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes la
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