Электронная библиотека (репозиторий) Томского государственного университета
Kapilevich, Leonid V.

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Add   Elevation of intracellular Na+ contributes to expression of early response genes triggered by endothelial cell shrinkage
Authors: Sidorenko, Svetlana V. | Fedorov, Dmitry | Klimanova, Elizaveta A. | Smolyaninova, Larisa V. | Kapilevich, Leonid V. | Grygorczyk, Ryszard | Orlov, Sergei N. | Shiyan, Alexandra A.
Source: Cellular physiology and biochemistry. 2019. Vol. 53, № 4. P. 638-647
Type: статьи в журналах
Date: 2019
Description: BACKGROUND/AIMS: Prolonged hyperosmotic shrinkage evokes expression of osmoprotective genes via nuclear factor NFAT5-mediated pathway and activates Na+ influx via hypertonicity-induced cation channels ... More
Add   Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling
Authors: Shiyan, Alexandra A. | Kapilevich, Leonid V. | Lopachev, Alexander V. | Fedorova, Tatiana N. | Klementieva, Tatiana S. | Moskovtsev, Aleksey A. | Kubatiev, Aslan A. | Orlov, Sergei N. | Smolyaninova, Larisa V.
Source: PLoS ONE. 2019. Vol. 14, № 9. P. e0222767 (1-23)
Type: статьи в журналах
Date: 2019
Description: It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other ... More
Add   Ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients in rodent cells: Physiological and pathophysiological implications
Authors: Sidorenko, Svetlana V. | Smolyaninova, Larisa V. | Kapilevich, Leonid V. | Gusakova, Svetlana V. | Lopina, Olga D. | Orlov, Sergei N. | Klimanova, Elizaveta A.
Source: Membrane transporters in the pathogenesis of cardiovascular and lung disorders. Cambridge [a. o.], 2019. P. 107-149
Type: статьи в сборниках
Date: 2019
Description: Elevation of [Na+]i/[K+]i-ratio is considered as one of the major signals triggering transcriptomic changes in various cells types. In this study, we identified ubiquitous and cell type-specific Na+,K ... More
Add   Transcriptomic changes in C2C12 myotubes triggered by electrical stimulation: Role of Ca2+i-mediated and Ca2+i-independent signaling and elevated [Na+]i/[K+]i ratio
Authors: Klimanova, Elizaveta A. | Milovanova, Kseniya | Lopina, Olga D. | Kapilevich, Leonid V. | Chibalin, Alexander V. | Orlov, Sergei N. | Sidorenko, Svetlana V.
Source: Cell calcium. 2018. Vol. 76. P. 72-86
Type: статьи в журналах
Date: 2018
Description: Elevation of Ca2+i and AMP-activated protein kinase (AMPK) are considered as major signals triggering transcriptomic changes in exercising skeletal muscle. Electrical pulse stimulation (EPS) of cultur ... More
Add   Changes in the plasma levels of myokines after different physical exercises in athletes and untrained individuals
Authors: Zakharova, Anna N. | Kabachkova, Anastasiya V. | Kironenko, Tatyana A. | Dyakova, Elena Yu. | Orlov, Sergei N. | Kapilevich, Leonid V.
Source: Human physiology. 2017. Vol. 43, № 3. P. 312-319
Type: статьи в журналах
Date: 2017
Description: The influence of dynamic and static load on the plasma level of myokines in strength-and endurance-trained athletes and untrained subjects has been studied. The range of myokines has been found to dep ... More
Add   Dynamic and static exercises differentially affect plasma cytokine content in elite endurance- and strength-trained athletes and untrained volunteers
Authors: Kapilevich, Leonid V. | Kabachkova, Anastasiya V. | Kironenko, Tatyana A. | Orlov, Sergei N. | Zakharova, Anna N.
Source: Frontiers in physiology. 2017. Vol. 8, Art. 35. P. 1-10
Type: статьи в журналах
Date: 2017
Description: Extensive exercise increases the plasma content of IL-6, IL-8, IL-15, leukemia inhibitory factor (LIF), and several other cytokines via their augmented transcription in skeletal muscle cells. However, ... More
Add   Electrical pulse stimulation decreases electrochemical Na+ and K+ gradients in C2C12 myotubes
Authors: Danilov, Kirill | Milovanova, Kseniya | Klimanova, Elizaveta | Kapilevich, Leonid V. | Orlov, Sergei N. | Sidorenko, Svetlana V.
Source: Biochemical and biophysical research communications. 2017. Vol. 493, № 2. P. 875-878
Type: статьи в журналах
Date: 2017
Description: Electrical pulse stimulation (EPS)-treated cultured myotubes are widely employed as an in vitro model of muscle contraction. Here we examined time-dependent EPS action and dose-dependent ouabain actio ... More
Add   Level of interleukins IL-6 and IL-15 in blood plasma of mice after forced swimming test
Authors: Kapilevich, Leonid V. | Zakharova, Anna N. | Kabachkova, Anastasiya V. | Orlov, Sergei N. | Kironenko, Tatyana A.
Source: Bulletin of experimental biology and medicine. 2017. Vol. 163, № 1. P. 10-13
Type: статьи в журналах
Date: 2017
Description: We measured the concentrations of IL-6 and IL-15 in blood plasma of mice at different terms after forced swimming, taking into account exercise intensity and preliminary training. It was shown that tr ... More
Add   Time- and dose dependent actions of cardiotonic steroids on transcriptome and intracellular content of Na+ and K+: a comparative analysis
Authors: Tverskoy, Artem M. | Koltsova, Svetlana V. | Sidorenko, Svetlana V. | Lopina, Olga D. | Tremblay, Johanne | Hamet, Pavel | Kapilevich, Leonid V. | Orlov, Sergei N. | Klimanova, Elizaveta A.
Source: Scientific Reports [Еlectronic resource]. 2017. Vol. 7. P. 45403 (1-11)
Type: статьи в журналах
Date: 2017
Description: Recent studies demonstrated that in addition to Na+,K+-ATPase inhibition cardiotonic steroids (CTSs) affect diverse intracellular signaling pathways. This study examines the relative impact of [Na+]i/ ... More
Add   Myokines as a promising marker of metabolic disorders and physical activity
Authors: Kapilevich, Leonid V. | Orlov, Sergei N. | Kabachkova, Anastasiya V.
Source: AIP Conference Proceedings. 2015. Vol. 1688. P. 030030-1-030030-4
Type: статьи в журналах
Date: 2015
Description: Currently, about 82 myokines identified and their number is increasing. It is shown that the major regulator of myokine expression and production is exercise. The expression level of IL-6 is dependent ... More
Add   NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension
Authors: Orlov, Sergei N. | Kapilevich, Leonid V. | Gusakova, Svetlana V. | Dulin, Nickolai O. | Koltsova, Svetlana V.
Source: Genes and diseases. 2015. Vol. 2, № 2. P. 186-196
Type: статьи в журналах
Date: 2015
Description: This review summarizes the data on the functional significance of ubiquitous (NKCC1) and renal-specific (NKCC2) isoforms of electroneutral sodium, potassium and chloride cotransporters. These carriers ... More
Add   Role of cytoskeleton network in anisosmotic volume changes of intact and permeabilized A549 cells
Authors: Platonova, Alexandra | Boudreault, Francis | Kapilevich, Leonid V. | Maksimov, Georgy V. | Grygorczyk, Ryszard | Orlov, Sergei N. | Ponomarchuk, Olga O.
Source: Biochimica et Biophysica Acta (BBA) – Biomembranes. 2015. Vol. 1848, № 10 (A). P. 2337-2343
Type: статьи в журналах
Date: 2015
Description: Recently we found that cytoplasm of permeabilized mammalian cells behaves as a hydrogel displaying intrinsic osmosensitivity. This study examined the role of microfilaments and microtubules in the reg ... More
Add   Skeletal muscle as an endocrine organ: Role of [Na+]i/[K+]i-mediated excitation-transcription coupling
Authors: Kapilevich, Leonid V. | Zakharova, Anna N. | Kotelevtsev, Yuri V. | Dulin, Nickolai O. | Orlov, Sergei N. | Kironenko, Tatyana A.
Source: Genes and diseases. 2015. Vol. 2, № 4. P. 328-336
Type: статьи в журналах
Date: 2015
Description: During the last two decades numerous research teams demonstrated that skeletal muscles function as an exercise-dependent endocrine organ secreting dozens of myokines. Variety of physiological and path ... More
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