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Source: Cellular physiology and biochemistry. 2019. Vol. 53, № 4. P. 638-647
Type: статьи в журналах
Date: 2019
Description:
BACKGROUND/AIMS: Prolonged hyperosmotic shrinkage evokes expression of osmoprotective genes via nuclear factor NFAT5-mediated pathway and activates Na+ influx via hypertonicity-induced cation channels
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Source: PLoS ONE. 2019. Vol. 14, № 9. P. e0222767 (1-23)
Type: статьи в журналах
Date: 2019
Description:
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other
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Source: Membrane transporters in the pathogenesis of cardiovascular and lung disorders. Cambridge [a. o.], 2019. P. 107-149
Type: статьи в сборниках
Date: 2019
Description:
Elevation of [Na+]i/[K+]i-ratio is considered as one of the major signals triggering transcriptomic changes in various cells types. In this study, we identified ubiquitous and cell type-specific Na+,K
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Source: Cell calcium. 2018. Vol. 76. P. 72-86
Type: статьи в журналах
Date: 2018
Description:
Elevation of Ca2+i and AMP-activated protein kinase (AMPK) are considered as major signals triggering transcriptomic changes in exercising skeletal muscle. Electrical pulse stimulation (EPS) of cultur
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Source: Human physiology. 2017. Vol. 43, № 3. P. 312-319
Type: статьи в журналах
Date: 2017
Description:
The influence of dynamic and static load on the plasma level of myokines in strength-and endurance-trained athletes and untrained subjects has been studied. The range of myokines has been found to dep
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Source: Frontiers in physiology. 2017. Vol. 8, Art. 35. P. 1-10
Type: статьи в журналах
Date: 2017
Description:
Extensive exercise increases the plasma content of IL-6, IL-8, IL-15, leukemia inhibitory factor (LIF), and several other cytokines via their augmented transcription in skeletal muscle cells. However,
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Source: Biochemical and biophysical research communications. 2017. Vol. 493, № 2. P. 875-878
Type: статьи в журналах
Date: 2017
Description:
Electrical pulse stimulation (EPS)-treated cultured myotubes are widely employed as an in vitro model of muscle contraction. Here we examined time-dependent EPS action and dose-dependent ouabain actio
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Source: Bulletin of experimental biology and medicine. 2017. Vol. 163, № 1. P. 10-13
Type: статьи в журналах
Date: 2017
Description:
We measured the concentrations of IL-6 and IL-15 in blood plasma of mice at different terms after forced swimming, taking into account exercise intensity and preliminary training. It was shown that tr
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Source: Scientific Reports [Еlectronic resource]. 2017. Vol. 7. P. 45403 (1-11)
Type: статьи в журналах
Date: 2017
Description:
Recent studies demonstrated that in addition to Na+,K+-ATPase inhibition cardiotonic steroids (CTSs) affect diverse intracellular signaling pathways. This study examines the relative impact of [Na+]i/
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Source: AIP Conference Proceedings. 2015. Vol. 1688. P. 030030-1-030030-4
Type: статьи в журналах
Date: 2015
Description:
Currently, about 82 myokines identified and their number is increasing. It is shown that the major regulator of myokine expression and production is exercise. The expression level of IL-6 is dependent
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Source: Genes and diseases. 2015. Vol. 2, № 2. P. 186-196
Type: статьи в журналах
Date: 2015
Description:
This review summarizes the data on the functional significance of ubiquitous (NKCC1) and renal-specific (NKCC2) isoforms of electroneutral sodium, potassium and chloride cotransporters. These carriers
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Source: Biochimica et Biophysica Acta (BBA) – Biomembranes. 2015. Vol. 1848, № 10 (A). P. 2337-2343
Type: статьи в журналах
Date: 2015
Description:
Recently we found that cytoplasm of permeabilized mammalian cells behaves as a hydrogel displaying intrinsic osmosensitivity. This study examined the role of microfilaments and microtubules in the reg
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Source: Genes and diseases. 2015. Vol. 2, № 4. P. 328-336
Type: статьи в журналах
Date: 2015
Description:
During the last two decades numerous research teams demonstrated that skeletal muscles function as an exercise-dependent endocrine organ secreting dozens of myokines. Variety of physiological and path
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