https://vital.lib.tsu.ru/vital/access/manager/Index ${session.getAttribute("locale")} 5 CNA landscape of breast tumor, connection with the efficiency of neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000662061 Wed 25 Sep 2019 11:02:44 KRAT ]]> Copy number aberrations landscape of a breast tumor, connection with the efficiency of neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000645071 Tue 18 Dec 2018 09:44:02 KRAT ]]> Predictive value of vascular endothelial growth factor receptor type 2 in triple-negative breast cancer patients treated with neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000651571 C (rs2071559) and KDR 1192G>A (rs2305948) polymorphisms. The pCR was used as an end-point in the treatment efficacy analysis. In the univariate analysis, the pCR rate was strongly associated with young age (P = 0.004), high Ki67 expression (P = 0.012), lymph node negativity (P = 0.023) as well as with positive VEGFR2 expression (P = 0.019) and the CAX regimen (P = 0.005). In the multivariate analysis, only patient’s age (P = 0.005) and pre-NCT VEGFR2 expression (P = 0.048) remained significant predictors of pCR. The pCR rate was higher in the CAX-treated patients than that in the FAC-treated patients (P = 0.005). Our results revealed that − 604TT genotype of rs2071559 and age < 50 years were correlated with a pCR in the CAX-treated patients. VEGFR2 expression in pre-NCT tumors and KDR gene polymorphism can be considered as additional predictive molecular markers of pCR in Russian TN breast cancer patients treated with NCT.]]> Tue 09 Apr 2019 14:51:05 KRAT ]]> Tumor-associated macrophages in human breast cancer produce new monocyte attracting and pro-angiogenic factor YKL-39 indicative for increased metastasis after neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000651305 Tue 07 May 2019 10:55:13 KRAT ]]> Predictive and prognostic significance of mRNA expression and DNA copies aberrations of ERCC1, RRM1, TOP1, TOP2A, TUBB3, TYMS, and GSTP1 genes in patients with breast cancer https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000925755 Thu 22 Dec 2022 09:58:42 KRAT ]]> Intratumoral morphological heterogeneity of breast cancer: Neoadjuvant chemotherapy efficiency and multidrug resistance gene expression https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000486173 Thu 13 Dec 2018 10:22:55 KRAT ]]> Heterogeneity of circulating tumor cells in neoadjuvant chemotherapy of breast cancer https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000787797 Mon 23 Nov 2020 09:53:07 KRAT ]]> Clonal evolution of a breast tumor during neoadjuvant chemotherapy and metastasis https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000578304 Mon 19 Nov 2018 12:08:25 KRAT ]]> Deletions of multidrug resistance gene loci in breast cancer leads to the down-regulation of its expression and predict tumor response to neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000553236 Mon 03 Dec 2018 09:35:44 KRAT ]]> Microarray analysis of DNA copy number aberration of the BRCA1 gene in breast tumor: correlation with the efficacy of neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000632335 Mon 01 Oct 2018 10:29:53 KRAT ]]> Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000634057 Fri 19 Oct 2018 16:10:00 KRAT ]]> DNA copy number aberrations and expression of ABC transporter genes in breast tumour: Correlation with the effect of neoadjuvant chemotherapy and prognosis of the disease https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001001438 Fri 19 May 2023 14:33:59 KRAT ]]>