Электронная библиотека (репозиторий) Томского государственного университета
неоадъювантная химиотерапия

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Add   Determination of BRCAness phenotype in breast tumors for the appointment of neoadjuvant chemotherapy based on platinum and taxanes
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Bragina, Olga D. | Karchevskaya, Ariana A. | Usynin, Evgeny A. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2023. Vol. 24, № 1. P. 207 (1-13)
Type: статьи в журналах
Date: 2023
Description: The concept of BRCAness was developed because of similarities between sporadic and hereditary breast cancer. BRCAness defines the pathogenesis and treatment sensitivity of many types of cancer, as wel ... More
Add   Mutations of BRCA1, BRCA2, and PALB2 genes in breast tumor tissue: Relationship with the effectiveness of neoadjuvant chemotherapy and disease prognosis
Authors: Tsyganov, Matvey M. | Sorokovikova, Sofia S. | Lutzkaya, Elizaveta A. | Ibragimova, Marina K.
Source: Genes. 2023. Vol. 14, № 8. P. 1554 (1-20)
Type: статьи в журналах
Date: 2023
Description: It has been shown that the loss of function of the BRCA1, BRCA2, and PALB2 genes due to a number of hereditary mutations or chromosomal aberrations can affect the effectiveness of chemotherapy treatme ... More
Add   DNA copy number aberrations and expression of ABC transporter genes in breast tumour: Correlation with the effect of neoadjuvant chemotherapy and prognosis of the disease
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Gaptulbarova, Kseniya A. | Tsydenova, Irina A. | Dolgasheva, Daria S. | Garbukov, Evgeny Yu. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Pharmaceutics. 2022. Vol. 14, № 5. P. 948 (1-19)
Type: статьи в журналах
Date: 2022
Description: One of the important reasons for the ineffectiveness of chemotherapy in breast cancer (BC) is considered to be the formation of a multidrug resistance phenotype in tumour cells, which is caused by the ... More
Add   Predictive and prognostic significance of mRNA expression and DNA copies aberrations of ERCC1, RRM1, TOP1, TOP2A, TUBB3, TYMS, and GSTP1 genes in patients with breast cancer
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Tsydenova, Irina A. | Gaptulbarova, Kseniya A. | Dolgasheva, Daria S. | Zdereva, Ekaterina A. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Diagnostics. 2022. Vol.12, № 2. P. 405 (1-15)
Type: статьи в журналах
Date: 2022
Description: Increasingly, many researchers are focusing on the sensitivity in breast tumors (BC) to certain chemotherapy drugs and have personalized their research based on the assessment of this sensitivity. One ... More
Add   Spatial transcriptomic analysis of tumor tissue in ovarian cancer patients treated with neoadjuvant chemotherapy
Authors: Larionova, Irina V. | Iamshchikov, Pavel | Rakina, Militsa | Villert, Alisa B. | Kolomiets, Larisa A. | Bezgodova, Natalia V.
Source: Annals of oncology. 2022. Vol. 33, suppl. 9. S1509
Type: статьи в журналах
Date: 2022
Add   Whole transcriptome analysis of breast cancer tumors during neoadjuvant chemotherapy: association with hematogenous metastasis
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2022. Vol. 23, № 22. P. 13906 (1-14)
Type: статьи в журналах
Date: 2022
Description: The assessment of molecular genetic landscape changes during NAC and the relationship between molecular signatures in residual tumors are promising approaches for identifying effective markers of outc ... More
Add   Полнотранскриптомный анализ опухоли молочной железы в процессе неоадъювантной химиотерапии: связь с ответом на предоперационную химиотерапию
Authors: Ибрагимова, Марина Константиновна | Цыганов, Матвей Михайлович | Литвяков, Николай Васильевич
Source: Успехи молекулярной онкологии. 2022. Т. 9, № 1. С. 33-41
Type: статьи в журналах
Date: 2022
Description: Введение. Лечение рака молочной железы во многих случаях включает системную химиотерапию в неоадъювантном режиме. Согласно данным литературы частота полного морфологического ответа опухоли значительно ... More
Add   Полнотранскриптомный анализ опухоли молочной железы в процессе неоадъювантной химиотерапии: связь с гематогенным метастазированием
Authors: Ибрагимова, Марина Константиновна | Цыденова, Ирина Александровна | Цыганов, Матвей Михайлович | Литвяков, Николай Васильевич
Source: VIII Международная научно-практическая конференция молодых ученых: биофизиков, биотехнологов, молекулярных биологов и вирусологов : сборник тезисов, Новосибирск, 2021. Новосибирск, 2021. С. 293-294
Type: статьи в сборниках
Date: 2021
Description: Важнейшим аспектом в современном подходе к лечению рака молочной железы (РМЖ) является мировой тренд в направле- нии прецизионной медицины, в том числе и в отношении неоадъювантной (предоперационной) ... More
Add   Исследование генов химиорезистентности у больных раком молочной железы при проведении неоадъювантной химиотерапии
Authors: Луцкая, Елизавета Андреевна
Source: Старт в науку : материалы LXIX научной студенческой конференции Биологического института, Томск, 20-24 апреля 2020 г.. Томск, 2020. С. 68
Type: статьи в сборниках
Date: 2020
Add   CNA landscape of breast tumor, connection with the efficiency of neoadjuvant chemotherapy
Authors: Tsyganov, Matvey M. | Deryusheva, Irina V. | Slonimskaya, Elena M. | Litvyakov, Nicolay V. | Ibragimova, Marina K.
Source: The 22nd International Charles Heidelberger symposium on cancer research : proceedings of the International symposium, 17-19 September 2018. Tomsk, 2018. P. 109-111
Type: статьи в сборниках
Date: 2018
Add   Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy
Authors: Tsyganov, Matvey M. | Larionova, Irina | Ibragimova, Marina K. | Deryusheva, Irina V. | Kazantseva, Polina V. | Slonimskaya, Elena M. | Frolova, Irina G. | Choinzonov, Evgeny L. | Cherdyntseva, Nadezhda V. | Litvyakov, Nicolay V. | Kzhyshkowska, Julia G.
Source: Cancer chemotherapy and pharmacology. 2018. Vol. 82, № 1. P. 99-109
Type: статьи в журналах
Date: 2018
Description: Purpose
Add   Heterogeneity of circulating tumor cells in neoadjuvant chemotherapy of breast cancer
Authors: Savelieva, Olga E. | Tashireva, Lubov A. | Tarabanovskaya, Natalia A. | Simolina, Elena I. | Denisov, Evgeny V. | Slonimskaya, Elena M. | Choynzonov, Evgeny L. | Perelmuter, Vladimir M. | Kaigorodova, Evgeniya V.
Source: Molecules. 2018. Vol. 23, № 4. P. 727 (1-10)
Type: статьи в журналах
Date: 2018
Description: The biological properties of circulating tumor cells (CTCs), and their dynamics during neoadjuvant chemotherapy are important, both for disease progression prediction and therapeutic target determinat ... More
Add   Predictive value of vascular endothelial growth factor receptor type 2 in triple-negative breast cancer patients treated with neoadjuvant chemotherapy
Authors: Zavyalova, Marina V. | Tarabanovskaya, Natalia A. | Dronova, Tatyana | Krakhmal, Nadezhda V. | Slonimskaya, Elena M. | Kzhyshkowska, Julia G. | Choynzonov, Evgeny L. | Cherdyntseva, Nadezhda V. | Babyshkina, Nataliya
Source: Molecular and cellular biochemistry. 2018. Vol. 444, № 1/2. P. 197-206
Type: статьи в журналах
Date: 2018
Description: The identification of informative biomarkers that could predict the treatment response is particularly important in the triple-negative (TN) breast cancer, which is characterized by biological diversi ... More
Add   The effect of neoadjuvant chemotherapy on the correlation of tumor-associated macrophages with CD31 and LYVE-1
Authors: Zavyalova, Marina V. | Riabov, Vladimir B. | Cherdyntseva, Nadezhda V. | Kzhyshkowska, Julia G. | Mitrofanova, Irina V.
Source: Immunobiology. 2018. Vol. 223, № 6/7. P. 449-459
Type: статьи в журналах
Date: 2018
Description: Angiogenesis and lymphangiogenesis play a crucial role in tumor growth, invasion and metastasis. Tumor-associated macrophages (TAM) induce both angiogenesis and lymphangiogenesis in mouse breast cance ... More
Add   Tumor-associated macrophages in human breast cancer produce new monocyte attracting and pro-angiogenic factor YKL-39 indicative for increased metastasis after neoadjuvant chemotherapy
Authors: Larionova, Irina | Litvyakov, Nicolay V. | Riabov, Vladimir B. | Zavyalova, Marina V. | Tsyganov, Matvey M. | Buldakov, Mikhail A. | Song, Bin | Moganti, Kondaiah | Kazantseva, Polina V. | Slonimskaya, Elena M. | Kremmer, Elisabeth | Flatley, Andrew | Klüter, Harald | Cherdyntseva, Nadezhda V. | Kzhyshkowska, Julia G. | Liu, Tengfei
Source: OncoImmunology. 2018. Vol. 7, № 6. P. e1436922-1-e1436922-17
Type: статьи в журналах
Date: 2018
Description: In breast cancer, the tumor microenvironment plays a critical role in the tumor progression and responses to therapy. Tumor-associated macrophages (TAMs) are major innate immune cells in tumor microen ... More

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