Impregnated graphite electrodes surface modification by metal nanoparticles (Au, Pt, Pd, Ni, Cu) from ethanol colloids obtained by laser ablation of metal targets in liquid without stabilizing agents was carried out. Electrochemical behavior of modified electrodes was explored using voltammetry. The possibility of its utilization in organic compounds analysis was evaluated using the example of the common analytes: ascorbic acid, dopamine, adrenaline, glucose and hydroquinone.