Электронная библиотека (репозиторий) Томского государственного университета
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Add   Determination of BRCAness phenotype in breast tumors for the appointment of neoadjuvant chemotherapy based on platinum and taxanes
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Bragina, Olga D. | Karchevskaya, Ariana A. | Usynin, Evgeny A. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2023. Vol. 24, № 1. P. 207 (1-13)
Type: статьи в журналах
Date: 2023
Description: The concept of BRCAness was developed because of similarities between sporadic and hereditary breast cancer. BRCAness defines the pathogenesis and treatment sensitivity of many types of cancer, as wel ... More
Add   Mutations of BRCA1, BRCA2, and PALB2 genes in breast tumor tissue: Relationship with the effectiveness of neoadjuvant chemotherapy and disease prognosis
Authors: Tsyganov, Matvey M. | Sorokovikova, Sofia S. | Lutzkaya, Elizaveta A. | Ibragimova, Marina K.
Source: Genes. 2023. Vol. 14, № 8. P. 1554 (1-20)
Type: статьи в журналах
Date: 2023
Description: It has been shown that the loss of function of the BRCA1, BRCA2, and PALB2 genes due to a number of hereditary mutations or chromosomal aberrations can affect the effectiveness of chemotherapy treatme ... More
Add   Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF
Authors: Larionova, Irina V. | Kiselev, Artem M. | Kazakova, Elena O. | Liu, Tengfei | Patysheva, Marina R. | Iamshchikov, Pavel | Liu, Quan | Mossel, Dieuwertje M. | Riabov, Vladimir B. | Rakina, Militsa A. | Sergushichev, Alexey | Bezgodova, Natalia V. | Vtorushin, Sergey V. | Litvyakov, Nicolay V. | Denisov, Evgeny V. | Koshkin, Philipp | Pyankov, Denis V. | Tsyganov, Matvey M. | Ibragimova, Marina K. | Cherdyntseva, Nadezhda V. | Kzhyshkowska, Julia G.
Source: Frontiers in immunology. 2023. Vol. 14. P. 1000497 (1-15)
Type: статьи в журналах
Date: 2023
Add   WNT-conditioned mechanism of exit from postchemotherapy shock of differentiated tumour cells
Authors: Tsydenova, Irina A. | Dolgasheva, Daria S. | Gaptulbarova, Kseniya A. | Ibragimova, Marina K. | Tsyganov, Matvey M. | Kravtsova, Ekaterina A. | Nushtaeva, Anna A. | Litvyakov, Nicolay V.
Source: Cancers. 2023. Vol. 15, № 10. P. 2765 (1-15)
Type: статьи в журналах
Date: 2023
Description: Metastatic disease is the leading cause of death in cancer patients. In our earlier clinical study of breast cancer patients, it was shown that metastasis after neoadjuvant chemotherapy and adjuvant h ... More
Add   DNA copy number aberrations and expression of ABC transporter genes in breast tumour: Correlation with the effect of neoadjuvant chemotherapy and prognosis of the disease
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Gaptulbarova, Kseniya A. | Tsydenova, Irina A. | Dolgasheva, Daria S. | Garbukov, Evgeny Yu. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Pharmaceutics. 2022. Vol. 14, № 5. P. 948 (1-19)
Type: статьи в журналах
Date: 2022
Description: One of the important reasons for the ineffectiveness of chemotherapy in breast cancer (BC) is considered to be the formation of a multidrug resistance phenotype in tumour cells, which is caused by the ... More
Add   Personalized prescription of chemotherapy based on assessment of mRNA expression of BRCA1, RRM1, ERCC1, TOP1, TOP2α, TUBβ3, TYMS, and GSTP1 genes in tumors compared to standard chemotherapy in the treatment of non-small-cell lung cancer
Authors: Tsyganov, Matvey M. | Rodionov, Evgeniy O. | Ibragimova, Marina K. | Miller, Sergey V. | Cheremisina, Olga V. | Frolova, Irina G. | Tuzikov, Sergey A. | Litvyakov, Nicolay V.
Source: Journal of personalized medicine. 2022. Vol. 12, № 10. P. 1647 (1-13)
Type: статьи в журналах
Date: 2022
Description: Objectives: A growing body of evidence suggests the important role of chemosensitive gene expression in the prognosis of patients with lung cancer. However, studies on combined gene expression assessm ... More
Add   Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Bragina, Olga D. | Zdereva, Ekaterina A. | Usynin, Evgeny A. | Litvyakov, Nicolay V.
Source: Сибирский онкологический журнал. 2022. Т. 21, № 5. С. 34-43
Type: статьи в журналах
Date: 2022
Description: ABC-transporter family genes have been well studied and their involvement in the development of drug resistance has been assessed. The presence of aberrant conditions in these genes can affect the tre ... More
Add   Predictive and prognostic significance of mRNA expression and DNA copies aberrations of ERCC1, RRM1, TOP1, TOP2A, TUBB3, TYMS, and GSTP1 genes in patients with breast cancer
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Tsydenova, Irina A. | Gaptulbarova, Kseniya A. | Dolgasheva, Daria S. | Zdereva, Ekaterina A. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Diagnostics. 2022. Vol.12, № 2. P. 405 (1-15)
Type: статьи в журналах
Date: 2022
Description: Increasingly, many researchers are focusing on the sensitivity in breast tumors (BC) to certain chemotherapy drugs and have personalized their research based on the assessment of this sensitivity. One ... More
Add   Stem gene expression in breast tumors during chemotherapy: Connection with the main clinical and morphological factors and the disease outcome
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Deryusheva, Irina V. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Journal of cancer research and therapeutics. 2022. Vol. 18, № 1. P. 89-95, [1]
Type: статьи в журналах
Date: 2022
Description: Introduction: In this research, we studied how the expression of 14 stem genes (TERT; OCT3; SMO; MYC; SNAI2; MOB3B; KLF4; BMI1; VIM; FLT3; LAT; SMAD2; LMNB2; KLF1), as well as the TGF-beta 1 cytokine ... More
Add   Tumour stem cells in breast cancer
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2022. Vol. 23, № 9. P. 5058 (1-21)
Type: статьи в журналах
Date: 2022
Description: Tumour stem cells (CSCs) are a self-renewing population that plays important roles in tumour initiation, recurrence, and metastasis. Although the medical literature is extensive, problems with CSC ide ... More
Add   Whole transcriptome analysis of breast cancer tumors during neoadjuvant chemotherapy: association with hematogenous metastasis
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2022. Vol. 23, № 22. P. 13906 (1-14)
Type: статьи в журналах
Date: 2022
Description: The assessment of molecular genetic landscape changes during NAC and the relationship between molecular signatures in residual tumors are promising approaches for identifying effective markers of outc ... More
Add   Human papillomavirus and ovarian cancer (review of literature and meta-analysis)
Authors: Ibragimova, Marina K. | Kokorina, E. V. | Tsyganov, Matvey M. | Churuksaeva, O. N. | Litvyakov, Nicolay V.
Source: Infection, genetics and evolution. 2021. Vol. 95. P. 105086 (1-6)
Type: статьи в журналах
Date: 2021
Description: Many factors are involved in carcinogenesis of the ovary, such human genetic and physiological characteristics as lifestyle, existing diseases of the reproductive system, and, as suggested, the human ... More
Add   In vitro modeling of tumor interclonal interactions using breast cancer cell lines
Authors: Bychkov, Vyacheslav A. | Pevzner, A. M. | Nebova, J. A. | Ermakova, Natalia N. | Ibragimova, Marina K. | Tsyganov, Matvey M. | Lyapunova, L. S. | Litvyakov, Nicolay V.
Source: Experimental oncology. 2021. Vol. 43, № 2. P. 118-124
Type: статьи в журналах
Date: 2021
Description: In the setting of limited resources, natural selection begins to occur between tumor clones. An experimental model of in vitro tumor heterogeneity would allow us to evaluate various types of biologica ... More
Add   Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy
Authors: Tsyganov, Matvey M. | Larionova, Irina | Ibragimova, Marina K. | Deryusheva, Irina V. | Kazantseva, Polina V. | Slonimskaya, Elena M. | Frolova, Irina G. | Choinzonov, Evgeny L. | Cherdyntseva, Nadezhda V. | Litvyakov, Nicolay V. | Kzhyshkowska, Julia G.
Source: Cancer chemotherapy and pharmacology. 2018. Vol. 82, № 1. P. 99-109
Type: статьи в журналах
Date: 2018
Description: Purpose
Add   Copy number aberrations landscape of a breast tumor, connection with the efficiency of neoadjuvant chemotherapy
Authors: Tsyganov, Matvey M. | Slonimskaya, Elena M. | Litvyakov, Nicolay V. | Ibragimova, Marina K.
Source: AIP Conference Proceedings. 2017. Vol. 1882. P. 020026-1-020026-5
Type: статьи в журналах
Date: 2017
Description: The research involved 80 patients diagnosed with breast cancer (BC). Each patient had their tumor biopsy material sampled before their treatment. We studied the tumor tissue using the CytoScan HD Arra ... More
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