In a study of breast cancer of 68 patients before and after neoadjuvant chemotherapy, overexpression in the residual tumor of 14/16 genes of the somato-stem transition was shown in patients with metastases that subsequently developed. This confirms our hypothesis about the important role of activation of the ability to somato-stem transition for tumor metastasis, which occurs under the influence of neoadjuvant chemotherapy. A new prognostic factor has been established, which makes it possible to predict the occurrence of hematogenous metastases with a sensitivity of 69%, a specificity of 94%, and a diagnostic accuracy of 82%.
Перспективы развития фундаментальных наук : сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, Россия, Томск, 24-27 апреля 2018 г.. Томск, 2018. Т. 4 : Биология и фундаментальная медицина. С. 110-112