This issue of Quantum Electronics presents the results of scientific research in a number of main directions related to the development of laser biophotonics. It contains 14 papers on topical problems of biophtonics, which represent the following fundamental and applied fields: terahertz spectroscopy and microscopy (M.R. Konnikova et al.; O.V. Minin and I.V. Minin), methods of high-resolution optical microscopy of cells and their laser manipulation (V. Richter et al.; P.B. Ermolinskiy et al.), methods of nonlinear optics and Raman spectroscopy of biological objects (E.A. Shirshin et al.; N.N. Brandt et al.), studies of viscoelastic properties of tissues using OCT (H. Zhang et al.), issues of control of optical properties of biological tissues (O.A. Zyuryukina et al.), methods of fluorescence diagnostics in problems of photodynamic therapy (I.P. Shilov et al.; A.V. Khilov et al.) and methods of laser photomodification of biological tissues and photoinactivation of viruses (A.V. Belikov et al.; N.Yu. Ignatieva et al.; I.N. Zavestovskaya et al.). One work, which will be published in the next issue, is devoted to the generation of silicon nanoparticles for biophotonic problems (V.Yu. Nesterov et al.). We also should emphasise that two of the presented works touch upon the problems associated with the study of the SARS-CoV-2 coronavirus in the study of both its properties (M.R. Konnikova et al.) and inactivation (I.N. Zavestovskaya et al.).