The in vivo quantitative assessment of the effectiveness of low-dose photodynamic therapy on wound healing using optical coherence tomography

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The in vivo quantitative assessment of the effectiveness of low-dose photodynamic therapy on wound healing using optical coherence tomography	58 MB	Adobe Acrobat PDF	Read	Download
DOI Доступ к ресурсу на сайте издателя			10.3390/pharmaceutics14020399

Title: The in vivo quantitative assessment of the effectiveness of low-dose photodynamic therapy on wound healing using optical coherence tomography
Creator: Zuhayri, Hala
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Nikolaev, Viktor V.
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Lepekhina, Tatiana B.
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Sandykova, Ekaterina A.
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Krivova, Natalya A.
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Kistenev, Yury V.
Date: 2022
DOI: 10.3390/pharmaceutics14020399
Description: The effect of low-dose photodynamic therapy on in vivo wound healing was investigated using optical coherence tomography. This work aims to develop an approach to quantitative assessment of the wound’s state during wound healing including the effect of low-dose photodynamic therapy using topical application of two different photosensitizers, 5-aminolevulinic acid and methylene blue, and two laser doses of 1 J/cm2 and 4 J/cm2. It was concluded that the laser dose of 4 J/cm2 was better compared to 1 J/cm2 and allowed the wound healing process to accelerate.