Fast estimation of the spectral optical properties of rabbit pancreas and pigment content analysis

doi:10.3390/photonics9020122

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Fast estimation of the spectral optical properties of rabbit pancreas and pigment content analysis	1 MB	Adobe Acrobat PDF	Read	Download
DOI Доступ к ресурсу на сайте издателя			10.3390/photonics9020122

#ткань поджелудочной железы

#оптические свойства

#коэффициент рассеяния

#коэффициент поглощения

#пигмент

Title: Fast estimation of the spectral optical properties of rabbit pancreas and pigment content analysis
Creator: Martins, Inês Soraia
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Silva, Hugo Filipe
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Tuchin, Valery V.
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Oliveira, Luís Manuel
Date: 2022
DOI: 10.3390/photonics9020122
Description: The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.