Samples of zinc-modified hydroxyapatite (HA) Ca(10 – x)Znx(PO4)6(OH)2 with different zinc content (x = 0.1 and 0.5) were synthesized by the liquid-phase method. It was found that the addition of zinc affects the original hydroxyapatite structure and changes the parameters of the crystal lattice. The materials obtained show antibacterial activity.