In vivo optical clearing of human skin under the effect of aqueous solutions of some monosaccharides

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In vivo optical clearing of human skin under the effect of aqueous solutions of some monosaccharides	4 MB	Adobe Acrobat PDF	Read	Download
DOI Доступ к ресурсу на сайте издателя			10.1117/12.2523317

Title: In vivo optical clearing of human skin under the effect of aqueous solutions of some monosaccharides
Creator: Berezin, Kirill V.
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Dvoretski, Konstantin N.
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Chernavina, Maria L.
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Nechaev, V. V.
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Lichter, A. M.
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Smirnov, Vladimir V.
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Antonova, Ekaterina M.
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Grechukhina, O. N.
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Kartashov, M. V.
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Tuchin, Valery V.
Date: 2019
DOI: 10.1117/12.2523317
Description: The results of in vivo optical immersion clearing of human skin under the effect of aqueous solutions of some immersion agents (monosaccharides of ribose, glucose and fructose, as well as glycerol, a triatomic alcohol) were obtained with the use of the OCT method. Values of average velocity of scattering coefficient change, obtained through an averaged Ascan of the OCT signal in the region of derma with the depth of 350 to 700 µm, were determined to evaluate the optical clearing efficiency. The velocity of scattering coefficient change and the optical clearing potential value appeared to be well correlated. The complex molecular modeling of a number of immersion clearing agents with a mimetic peptide of collagen (GPH)3, carried out with the use of the methods of classical molecular dynamics and quantum chemistry, allowed to identify correlations between the optical clearing efficiency and such a property as the energy of intermolecular interaction of clearing agents with a collagen peptide fragment.

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collection(s): Физический факультет
Identifier: смотреть в электронном каталоге НБ ТГУ
Type: статьи в журналах
Source: Proceedings of SPIE. 2019. Vol. 11066 : Saratov fall meeting 2018 : Laser physics, photonic technologies, and molecular modeling. P. 110661D-1-110661D-8
Language: eng

Created: 18-05-2021

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Физический факультет In vivo optical clearing of human skin under the effect of aqueous solutions of some monosaccharides