Comparative study into the effect of detector noises and sensitivity on the serum SERS analysis: Example of non-communicable diseases discrimination

doi:10.1002/jbio.202400475

Эндаумент фонд ТГУ!
Впиши своё имя в историю университета
- Сделать пожертвование -

Add to "Quick Collection"

Description	Size	Format
Сomparative study into the effect of detector noises and sensitivity on the serum SERS analysis: Example of non-communicable diseases discrimination	667 KB	Adobe Acrobat PDF	Read	Download
DOI Доступ к ресурсу на сайте издателя			10.1002/jbio.202400475

#сыворотка крови

#хроническая сердечная недостаточность

#хроническая обструктивная болезнь легких

#рамановская спектроскопия

#спектральный анализ

#поверхностно-усиленная рамановская спектроскопия

Title: Comparative study into the effect of detector noises and sensitivity on the serum SERS analysis: Example of non-communicable diseases discrimination
Creator: Bratchenko, Lyudmila A.
|
Khristoforova, Yulia A.
|
Pimenova, Irina A.
|
Snegerev, Mikhail S.
|
Kupaev, Vitaly I.
|
Lebedev, Petr A.
|
Kistenev, Yury V.
|
Bratchenko, Ivan A.
Date: 2025
DOI: 10.1002/jbio.202400475
Description: The aim of the study is to compare the performance of surface-enhanced Raman spectroscopy (SERS) analysis of serum using a non-cooled detector (EnSpectr R785) and a high spectral resolution detector (Renishaw) in the task of discrimination between the patients with chronic heart failure and the patients with chronic obstructive pulmonary disease. The SERS-based solution of the classification problem demonstrates an insignificant relationship between the disease classification accuracy and detector quality (classification accuracy for the high-resolution setup is 0.84 and for the low-cost setup is 0.81). In the data recorded on Renishaw setup, the most significant bands are 611, 675, 720, 804, 1187, 1495, and 1847 cm−1; for the EnSpectr setup—721, 1051, and 1665 cm−1. The results have revealed equal discrimination capabilities in the EnSpectr and the Renishaw setups; however, the Renishaw setup has more prospects for identifying the spectral contribution of pathologically associated analytes.

Relationships: Show Relationship Browser for this Object
collection(s): Физический факультет | Научное управление
Identifier: смотреть в электронном каталоге НБ ТГУ
Relation: Journal of biophotonics
Type: статьи в журналах
Source: Journal of biophotonics. 2025. Vol. 18, № 4. P. e202400475 (1-8)
Language: eng

Created: 27-10-2025

35 Visitors

37 Hits

7 Downloads

Научное управление

Физический факультет Comparative study into the effect of detector noises and sensitivity on the serum SERS analysis: Example of non-communicable diseases discrimination