https://vital.lib.tsu.ru/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000578196 Wed 28 Jun 2017 10:01:41 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000461356 Wed 27 Sep 2017 09:59:25 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000720380 Wed 20 May 2020 10:23:06 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000645262 G) were similar in healthy Siberian women (n = 136) and cancer patients (n = 129) (A0,73:G0,27) and intermediate between the European and Asian populations, while genotype distributions were different, with the increase of AG rate in breast cancer patients (OR = 1.76; 95% CI = 1.04–1.90; P(Y) = 0.035 χ2 = 4.44). Heterozygous AG genotype was associated with tumour size (OR = 3.67, P(Y) = 0.004), ER-negative tumours (OR = 3.25, P(Y) = 0.0028), triple-negative tumours (OR = 4.94, P(Y) = 0.015) but not menopausal status, PR and HER-2 status, local or distant metastasis. Homozygous GLCE genotypes (AA/GG) were more common for ER + PR + luminal A breast cancer (OR = 0.25, P(Y) = 0.031). Loss-of-heterozigosity was identified in 5 of 51 breast tumours and the loss of G allele was associated with the decreased GLCE expression. Epidemiologic data for the GLCE SNP in different racial/ethnic groups demonstrated high AG genotype rates as a risk factor not for breast cancer incidence but for poor prognosis of the disease. The obtained data suggest an involvement of GLCE rs3865014 in breast cancer development. Heterozygous AG genotype might be a risk factor for breast cancer susceptibility in Siberian women and is associated with aggressive ER-negative and triple-negative cancer subtypes.]]> Wed 19 Dec 2018 14:12:22 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000626410 Wed 16 May 2018 11:25:19 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000486846 Wed 06 Sep 2017 13:36:09 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000847004 Wed 02 Mar 2022 14:12:25 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000616011 Tue 28 Nov 2017 10:35:19 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000433925 Tue 26 Sep 2017 09:22:14 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001130910 Tue 12 Mar 2024 09:32:38 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000584034 Tue 07 Nov 2017 09:42:51 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000667784 Tue 05 Nov 2019 16:00:25 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000327830 Thu 29 Jun 2023 10:35:04 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000470760 Thu 29 Jun 2017 13:34:11 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000515821 Thu 29 Jun 2017 13:20:01 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000723948 Thu 17 Sep 2020 12:36:18 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000465639 Thu 14 Sep 2017 15:23:18 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000502267 Thu 06 Jul 2017 10:53:03 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000505665 Thu 06 Jul 2017 10:32:07 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000451416 Mon 25 Sep 2017 10:44:03 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000540322 Mon 19 Mar 2018 12:30:00 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000524697 Mon 14 Jan 2019 12:16:37 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001117537 Mon 12 Feb 2024 09:26:21 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000723500 Mon 07 Sep 2020 11:21:15 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000486964 Mon 02 Oct 2017 12:29:09 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000448213 Mon 02 Oct 2017 12:22:22 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000448200 Fri 29 Sep 2017 09:28:14 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000518118 Fri 25 Aug 2017 13:14:03 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000707673 Fri 20 Mar 2020 14:31:09 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000892222 Fri 15 Apr 2022 15:07:24 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000499263 Fri 07 Jul 2017 11:17:17 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000789055 Fri 04 Dec 2020 09:54:03 KRAT ]]> https://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000635286 Fri 02 Nov 2018 09:58:47 KRAT ]]>