Solid-state active laser media using PMMA matrices doped by Chromene-3 and PM-567 were created. Their lasing and spectral properties are investigated. Fluorescence bandwidth is wide enough for tunability (near 40 nm full-width on the half maximum - FWHM). The photostability is number of the pulses in one dot needed to decrease efficiency twice – near of 3*105 pulses are obtained. The obtained data lead to the development of the tunable solid-state laser on the basis of the investigated LAE demanded in medicine.