It has been studied ZrO2(MexOy) based porous ceramics, obtained from the powders consisting of hollow spherical particles. It was shown that the structure is represented as a cellular carcass with a bimodal porosity, formed of a large pore close to a spherical shape and the pores that were not filled with the powder particles during the compaction. For such ceramics the increase of pore volume is accompanied by an increase in strain in an elastic area. It was also shown that the porous ZrO2 ceramics had no acute or chronic cytotoxicity. At the same time, ceramics possess the osteoconductive properties: adhesion support, spreading, proliferation and osteogenic differentiation of MSCs.