Background: Promoting role of tumor-associated macrophages (TAM) in angiogenesis and lymphangiogenesis was demonstrated in mouse tumor model sand human cancers. However, our latest studies revealed that amount of TAM in patients with breast cancer before as well after neoadjuvant chemotherapy (NAC) reversely correlated with lymphatic metastasis. Our aim was to analyse the effect of NAC on correlation of TAM in intratumoral compartments with angiogenesis and lymphangiogenesis.
Annals of oncology. 2017. Vol. 28, Supplement 5. P. 581-582
Language
eng
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НИИ биологии и биофизики
Effect of neoadjuvant chemotherapy on correlation of tumor-associated macrophages with angiogenesis and lymphangiogenesis in human breast cancer