Электронная библиотека (репозиторий) Томского государственного университета

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Add   Determination of BRCAness phenotype in breast tumors for the appointment of neoadjuvant chemotherapy based on platinum and taxanes
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Bragina, Olga D. | Karchevskaya, Ariana A. | Usynin, Evgeny A. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2023. Vol. 24, № 1. P. 207 (1-13)
Type: статьи в журналах
Date: 2023
Description: The concept of BRCAness was developed because of similarities between sporadic and hereditary breast cancer. BRCAness defines the pathogenesis and treatment sensitivity of many types of cancer, as wel ... More
Add   Mutations of BRCA1, BRCA2, and PALB2 genes in breast tumor tissue: Relationship with the effectiveness of neoadjuvant chemotherapy and disease prognosis
Authors: Tsyganov, Matvey M. | Sorokovikova, Sofia S. | Lutzkaya, Elizaveta A. | Ibragimova, Marina K.
Source: Genes. 2023. Vol. 14, № 8. P. 1554 (1-20)
Type: статьи в журналах
Date: 2023
Description: It has been shown that the loss of function of the BRCA1, BRCA2, and PALB2 genes due to a number of hereditary mutations or chromosomal aberrations can affect the effectiveness of chemotherapy treatme ... More
Add   DNA copy number aberrations and expression of ABC transporter genes in breast tumour: Correlation with the effect of neoadjuvant chemotherapy and prognosis of the disease
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Gaptulbarova, Kseniya A. | Tsydenova, Irina A. | Dolgasheva, Daria S. | Garbukov, Evgeny Yu. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Pharmaceutics. 2022. Vol. 14, № 5. P. 948 (1-19)
Type: статьи в журналах
Date: 2022
Description: One of the important reasons for the ineffectiveness of chemotherapy in breast cancer (BC) is considered to be the formation of a multidrug resistance phenotype in tumour cells, which is caused by the ... More
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