Электронная библиотека (репозиторий) Томского государственного университета

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Add   Cardioprotective effects of a selective c-Jun N-terminal kinase inhibitor in a rat model of myocardial infarction
Authors: Plotnikov, Mark B. | Chernysheva, Galina A. | Smolyakova, Vera I. | Aliev, Oleg I. | Fomina, Tatyana I. | Sandrikina, Lyubov A. | Sukhodolo, Irina V. | Ivanova, Vera V. | Osipenko, Anton N. | Anfinogenova, Nina D. | Khlebnikov, Andrei I. | Atochin, Dmitriy N. | Schepetkin, Igor A. | Quinn, Mark T.
Source: Biomedicines. 2023. Vol. 11, № 3. P. 714 (1-15)
Type: статьи в журналах
Date: 2023
Description: Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial infarction (MI). The aim of this research was ... More
Add   Rotational barriers in N-benzhydrylformamides: An NMR and DFT study
Authors: Sadvakassova, Madina Zh. | Khlebnikov, Andrei I. | Bakibaev, Abdigali A. | Kotelnikov, Oleg A. | Erkasov, Rakhmetulla Sh. | Yelubay, Madeniyet A. | Issabayeva, Manar A.
Source: Molecules. 2023. Vol. 28, № 2. P. 535 (1-13)
Type: статьи в журналах
Date: 2023
Description: N-Benzhydrylformamides are pharmacologically active compounds with anticonvulsant, enzyme-inducing, antihypoxic, and other types of biological activity. The conformational behavior of benzhydrylformam ... More
Add   Suppression of age-related macular degeneration-like pathology by c-Jun N-terminal kinase inhibitor IQ-1S
Authors: Zhdankina, Anna A. | Tikhonov, Dmitry I. | Logvinov, Sergey V. | Plotnikov, Mark B. | Khlebnikov, Andrei I. | Kolosova, Natalia G.
Source: Biomedicines. 2023. Vol. 11, № 2. P. 395 (1-16)
Type: статьи в журналах
Date: 2023
Description: Age-related macular degeneration (AMD) is the leading cause of irreversible visual impairment worldwide. The development of AMD is associated with inflammation, oxidative stress, and progressive prote ... More
Add   Neuroprotective effects of the lithium salt of a novel JNK inhibitor in an animal model of cerebral ischemia-reperfusion
Authors: Schepetkin, Igor A. | Chernysheva, Galina A. | Aliev, Oleg I. | Kirpotina, Liliya N. | Smolyakova, Vera I. | Osipenko, Anton N. | Plotnikov, Mark B. | Kovrizhina, Anastasia R. | Khlebnikov, Andrei I. | Plotnikov, Evgeny V. | Quinn, Mark T.
Source: Biomedicines. 2022. Vol. 10, № 9. P. 2119 (1-16)
Type: статьи в журналах
Date: 2022
Add   Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors
Authors: Cantini, Niccolò | Khlebnikov, Andrei I. | Crocetti, Letizia | Schepetkin, Igor A. | Floresta, Giuseppe | Guerrini, Gabriella | Vergelli, Claudia | Bartolucci, Gianluca | Quinn, Mark T. | Giovannoni, Maria Paola
Source: Bioorganic & medicinal chemistry. 2021. Vol. 29. P. 115836 (1-17)
Type: статьи в журналах
Date: 2021
Description: Human neutrophil elastase (HNE) is a potent protease that plays an important physiological role in many processes but is also involved in a variety of pathologies that affect the pulmonary system. Thu ... More
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