Электронная библиотека (репозиторий) Томского государственного университета
2022

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Add   DNA copy number aberrations and expression of ABC transporter genes in breast tumour: Correlation with the effect of neoadjuvant chemotherapy and prognosis of the disease
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Gaptulbarova, Kseniya A. | Tsydenova, Irina A. | Dolgasheva, Daria S. | Garbukov, Evgeny Yu. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Pharmaceutics. 2022. Vol. 14, № 5. P. 948 (1-19)
Type: статьи в журналах
Date: 2022
Description: One of the important reasons for the ineffectiveness of chemotherapy in breast cancer (BC) is considered to be the formation of a multidrug resistance phenotype in tumour cells, which is caused by the ... More
Add   Personalized prescription of chemotherapy based on assessment of mRNA expression of BRCA1, RRM1, ERCC1, TOP1, TOP2α, TUBβ3, TYMS, and GSTP1 genes in tumors compared to standard chemotherapy in the treatment of non-small-cell lung cancer
Authors: Tsyganov, Matvey M. | Rodionov, Evgeniy O. | Ibragimova, Marina K. | Miller, Sergey V. | Cheremisina, Olga V. | Frolova, Irina G. | Tuzikov, Sergey A. | Litvyakov, Nicolay V.
Source: Journal of personalized medicine. 2022. Vol. 12, № 10. P. 1647 (1-13)
Type: статьи в журналах
Date: 2022
Description: Objectives: A growing body of evidence suggests the important role of chemosensitive gene expression in the prognosis of patients with lung cancer. However, studies on combined gene expression assessm ... More
Add   Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Bragina, Olga D. | Zdereva, Ekaterina A. | Usynin, Evgeny A. | Litvyakov, Nicolay V.
Source: Сибирский онкологический журнал. 2022. Т. 21, № 5. С. 34-43
Type: статьи в журналах
Date: 2022
Description: ABC-transporter family genes have been well studied and their involvement in the development of drug resistance has been assessed. The presence of aberrant conditions in these genes can affect the tre ... More
Add   Predictive and prognostic significance of mRNA expression and DNA copies aberrations of ERCC1, RRM1, TOP1, TOP2A, TUBB3, TYMS, and GSTP1 genes in patients with breast cancer
Authors: Tsyganov, Matvey M. | Ibragimova, Marina K. | Garbukov, Evgeny Yu. | Tsydenova, Irina A. | Gaptulbarova, Kseniya A. | Dolgasheva, Daria S. | Zdereva, Ekaterina A. | Frolova, Anastasia A. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Diagnostics. 2022. Vol.12, № 2. P. 405 (1-15)
Type: статьи в журналах
Date: 2022
Description: Increasingly, many researchers are focusing on the sensitivity in breast tumors (BC) to certain chemotherapy drugs and have personalized their research based on the assessment of this sensitivity. One ... More
Add   Stem gene expression in breast tumors during chemotherapy: Connection with the main clinical and morphological factors and the disease outcome
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Deryusheva, Irina V. | Slonimskaya, Elena M. | Litvyakov, Nicolay V.
Source: Journal of cancer research and therapeutics. 2022. Vol. 18, № 1. P. 89-95, [1]
Type: статьи в журналах
Date: 2022
Description: Introduction: In this research, we studied how the expression of 14 stem genes (TERT; OCT3; SMO; MYC; SNAI2; MOB3B; KLF4; BMI1; VIM; FLT3; LAT; SMAD2; LMNB2; KLF1), as well as the TGF-beta 1 cytokine ... More
Add   Tumour stem cells in breast cancer
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2022. Vol. 23, № 9. P. 5058 (1-21)
Type: статьи в журналах
Date: 2022
Description: Tumour stem cells (CSCs) are a self-renewing population that plays important roles in tumour initiation, recurrence, and metastasis. Although the medical literature is extensive, problems with CSC ide ... More
Add   Whole transcriptome analysis of breast cancer tumors during neoadjuvant chemotherapy: association with hematogenous metastasis
Authors: Ibragimova, Marina K. | Tsyganov, Matvey M. | Litvyakov, Nicolay V.
Source: International journal of molecular sciences. 2022. Vol. 23, № 22. P. 13906 (1-14)
Type: статьи в журналах
Date: 2022
Description: The assessment of molecular genetic landscape changes during NAC and the relationship between molecular signatures in residual tumors are promising approaches for identifying effective markers of outc ... More
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