This study presents the method of HPLC separation of cis- and trans-4,5-dihydroxyimidazolidine-2- thione stereoisomers. Different columns were used for this study, but the best separation was achieved by using the HILIC column. This method allows to determine the ratio between isomers and impurities included in the sample. Also, existence of cis- and trans isomers and its ratio were determined by 1H NMR spectroscopy. The results, obtained by the NMR agrees with the results obtained by using our HPLC method.
Перспективы развития фундаментальных наук : сборник научных трудов XIV Международной конференции студентов, аспирантов и молодых ученых, Россия, Томск, 25-28 апреля 2017 г.. Томск, 2017. Т. 2 : Химия. С. 307-309